Aim. The aim of this study was to determine the effect of first phase cardiac rehabilitation

programs on anxiety and depression in acute coronary syndrome (ACS) patients.

Background. Anxiety and depression are psychological factors influencing the prognosis,

recovery, and adherence to treatment in patients with ACS. Cardiac rehabilitation programs are

an important part of the care plan is arranged for the majority of heart patients.

Method. This clinical trial study was conducted on 88 ACS patients with regard to the inclusion

criteria. The subjects were randomly divided to experimental (n=44) and control (n=44) groups.

The experimental group participated in four educational sessions of cardiac rehabilitation

program, which included familiarity with risk factors of heart disease, nutrition and drugs

recommendations, stress and depression reduction methods and exercises training. Information

booklet was given at the end of the sessions. Data were collected by demographic and diseaserelated

questionnaires and Persian version of Hospital Anxiety Depression Score (HADS).The

data were analyzed by SPSS software version 16.0 and descriptive and analytic statistical tests

(Independent t-test and Chi-square and Fisher's exact test).

Finding. The findings showed that there was no statistically significant relationship of

demographic and disease-related information with anxiety and depression scores before study.

There was significant statistical difference between two groups in the mean of anxiety and

depression score after intervention (P_0.0001).

Conclusion. According to the finding, the first phase cardiac rehabilitation programs is effective

in reducing anxiety and depression in ACS patients Therefore, it can be an effective way to plan

nursing care of patients with ACS.